Comprehensive Interactome Profiling for Screening & Optimizing RNA Binders with High Affinity & Selectivity
Time: 3:30 pm
day: Conference Day One
Details:
- Highly structured RNA exhibit potential for high affinity with small molecules
- vitro interactome profiling of 30,000~ drug-like compounds vs. 2,000~ RNA structures extracted from disease related RNA
- SAR analyses of target binding modes at single-nucleotide resolution and binding selectivity among compound derivatives
