Discovery of Selective RNA Binders Through a Quantitative High Throughput Primary Biochemical Screen
Time: 3:00 pm
day: Conference Day One
Details:
- Utilizing biophysical design methods to develop RNA switch-based sensors to identify compounds that modulate target RNA structure
- Rapidly generating highly quantitative datasets on binding and selectivity of compound libraries against RNA targets
- Leveraging machine learning models trained on highly quantitative HTS data to generate novel binders for RNAs through virtual screening of millions of molecules
